microwave enhanced knoevenagel condensation of barbituric acid with aromatic aldehydes on basic alumina

Microwave Enhanced Knoevenagel Condensation of Barbituric Acid with Aromatic Aldehydes on Basic Alumina

Efficient Knoevenagel condensation of barbituric acid with different aromatic aldehydes on basic alumina was performed in a conventional microwave over in the absence of solvent.

Kinetic Studies of Condensation of Aromatic Aldehydes with Meldrum’s Acid

The condensation reaction of Meldrum’s acid with aromatic aldehydes in the presence of a catalyst has been investigated spectrophotometrically at 25Ð50 ∞C. The reaction follows overall second order kinetics, first order in each of the reactants. Electron-withdrawing groups accelerate and electron-releasing groups retard the rate of condensation. From the dependence of the rate constants on temp...

The Condensation of Aromatic Aldehydes with Glycine and Acetylglycine

The Condensation of Aromatic Aldehydes with Glycine and Acetylglycine

Synthesis of fused uracils: pyrano[2,3-d]pyrimidines and 1,4-bis(pyrano[2,3-d]pyrimidinyl)benzenes by domino Knoevenagel/Diels-Alder reactions

ABSTRACT Knoevenagel condensation of barbituric acids with aromatic aldehydes containing one or two formyl groups was carried out. 5-Arylidenebarbituric acids underwent smooth hetero-Diels-Alder (HDA) reactions with enol ethers to afford cis and trans diastereoisomers of pyrano[2,3-d]pyrimidine-2,4-diones and 5,5'-(1,4-phenylene)bis[2H-pyrano[2,3-d]pyrimidine-2,4(3H)-dione] derivatives in excel...

BF3/nano-γ-Al2O3 Promoted Knoevenagel Condensation at Room Temperature

The Knoevenagel condensation of aromatic aldehydes with barbituric acid, dimedone and malononitrile occurred in the presence of BF3/nano-γ-Al2O3 at room temperature in ethanol. This catalyst is characterized by powder X-ray diffraction (XRD), fourier transform infrared spectroscopy (FT-IR), thermal gravimetric analysis (TGA), field emission scanning electron microscopy (FESEM) and energy-disper...